A curated stream of the latest cancer-research findings and science news from reputable international sources — fetched automatically and summarized. Follow the link on each item to read the full article at its original source.
A controlled mouse study has provided direct evidence that inherited genetics can steer how cancer begins and evolves after DNA damage. The discovery could eventually help doctors better predict cancer risk and tailor screening and treatments to each patient.
Read full article at source →Scientists used CRISPR to make prostate cancer cells easier for the immune system to detect and destroy. The experimental treatment dramatically improved the effects of immunotherapy in mice and may offer hope for other hard-to-treat tumors.
Read full article at source →Researchers are applying evolutionary theory to cancer by changing treatments before tumors have time to develop resistance. Mathematical models suggest that rapid, carefully timed switches between multiple therapies could improve cure rates.
Read full article at source →Immune checkpoint inhibitors have revolutionized cancer treatment, helping people with advanced melanoma, lung cancer, bladder cancer, and other cancers live longer, healthier lives. This is the story of how decades of NCI-funded research made these breakthrough immunotherapy drugs possible.
Read full article at source →Scientists uncovered how influenza A commandeers human cells, including a surprising strategy that dissolves tiny structures in the nucleus and releases proteins the virus may use to reproduce. The detailed molecular map could reveal new drug targets and help researchers…
Read full article at source →A naturally occurring compound found in foods such as wheat germ, mushrooms, and aged cheese may help older adults build stronger protection after vaccination. In a small pilot trial, researchers gave spermidine supplements to adults over 65 following their third…
Read full article at source →Scientists may have uncovered one reason coffee is repeatedly associated with healthier aging and lower disease risk. Compounds in coffee appear to activate NR4A1, a receptor that helps protect cells from stress, inflammation, and damage. These protective effects disappeared when…
Read full article at source →Researchers solved a long-standing mystery behind how a bacterial toxin associated with colorectal cancer damages the colon. The toxin first binds to a receptor called claudin-4, giving it access to attack the cells' protective barrier. After identifying this weak point,…
Read full article at source →An unusual leopard gecko that naturally develops aggressive tumors may become an important new model for cancer research. Scientists found its tumors share key genetic changes with human cancers, offering a rare opportunity to study the disease as it develops…
Read full article at source →A major review found that people who consumed the most chili peppers had a substantially higher risk of esophageal cancer, though the evidence was less clear for stomach and colorectal cancers. Researchers emphasize that the findings show an association, not…
Read full article at source →An unexpected study found that young non-smokers with healthier diets had higher rates of lung cancer, raising questions about whether pesticide exposure from conventionally grown produce could play a role. Researchers stress that the findings are preliminary and require further…
Read full article at source →Researchers found that the common blood pressure drug telmisartan can significantly improve the performance of the cancer drug olaparib, potentially expanding its benefits beyond patients with BRCA-related tumors. The combination is already being tested in human clinical trials after showing…
Read full article at source →Heavy marijuana smoking may raise the risk of lung cancer and several head and neck cancers, according to growing research, but many important questions remain unanswered. Scientists are still trying to determine how much marijuana use is enough to significantly…
Read full article at source →A naturally occurring bacterium from amphibian intestines completely eliminated colorectal tumors in mice with a single treatment by both attacking cancer cells and activating the immune system. The findings point to a promising new type of cancer therapy that could…
Read full article at source →Researchers found that mRNA cancer vaccines can recruit an unexpected immune cell to launch powerful tumor-fighting responses, overturning a long-held assumption about how the vaccines work. The discovery could lead to more effective cancer vaccines and help scientists tailor treatments…
Read full article at source →A surprising discovery is reshaping scientists' understanding of how humans develop sharp central vision before birth. Instead of blue cone cells migrating away from the retina's center, the study found they transform into red and green cones under the influence…
Read full article at source →Tiny silica nanoparticles engineered to seek out prostate cancer caused tumor cells to self-destruct and supercharged the immune system in preclinical mouse studies. Combined with immunotherapy, the treatment produced complete remissions in multiple mice, raising hopes for a powerful new…
Read full article at source →Researchers have cracked the code behind bacteria's ability to naturally manufacture multiple versions of powerful anti-cancer drugs. The discovery could make it much easier to engineer new cancer treatments inspired by nature, including improved versions of existing medicines.
Read full article at source →Scientists have discovered that creatine may strengthen one of the immune system's most important cancer-fighting pathways by energizing dendritic cells that activate killer T cells. The promising results could eventually help make immunotherapy more effective, but they have not yet…
Read full article at source →Scientists at the University of Illinois Chicago have turned an unlikely source into a potential new weapon against cancer: bacteria that naturally live inside tumors. They developed a peptide called aurB, inspired by a bacterial protein, that infiltrates cancer cells…
Read full article at source →A new study suggests that apoB, a blood test that measures harmful cholesterol particles, is better than standard LDL cholesterol testing for deciding who needs more intensive treatment. Researchers found it could prevent more heart attacks and strokes while remaining…
Read full article at source →Researchers discovered an “Achilles’ heel” shared by E. coli, Shigella, and other diarrhea-causing bacteria: enzymes they use to breach the gut’s protective mucus layer. By targeting this common vulnerability, scientists may be able to develop a single vaccine that prevents…
Read full article at source →Some cancer cells evade treatment by entering a dormant state triggered by stress hormones. ETH Zurich scientists have created a light-controlled molecular switch that selectively destroys the receptors responsible for this survival mode. In laboratory lung cancer cells, the approach…
Read full article at source →A UCLA study has identified a hidden Achilles' heel in aggressive small cell cancers that have resisted new treatments for decades. Scientists found that tumors lacking the RB gene become critically dependent on the protein E2F3 for survival. Blocking E2F3…
Read full article at source →A new intranasal DNA vaccine may give the immune system an extra weapon against tuberculosis by targeting bacteria that can hide from antibiotics. In animal studies, it helped clear infections faster, reduced lung inflammation, and prevented relapse after treatment. The…
Read full article at source →Could something as simple as vitamin C help support a healthier aging brain? In a study of more than 2,000 older adults in Japan, researchers found that people with lower vitamin C levels in their blood also tended to have…
Read full article at source →Scientists at the University of Oxford have created a calculator that predicts a person's individual risk of serious muscle disorders from statin medications. Their analysis found that more than 98% of people who qualify for statins are at low risk…
Read full article at source →A new stem-cell-inspired technique allows scientists to grow vast numbers of immune-cell progenitors that can be engineered to hunt cancer and strengthen immune responses. In animal studies, the cells fought tumors, restored immune function, and showed promise as a durable,…
Read full article at source →Researchers tested experimental PCAI compounds against pancreatic cancer cells and found they had powerful anticancer effects. One leading compound blocked more than 90% of cancer cell migration, suggesting it could help prevent the spread of tumors. Rather than suppressing cancer…
Read full article at source →Researchers have identified a vitamin B12–based compound that can cross the blood-brain barrier and home in on glioblastoma tumors. In animal studies, the compound accumulated preferentially in tumor tissue and delivered sustained nitric oxide directly to cancer cells. It also…
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